How does the appearance of gastric, pancreatic, and intestinal mucosa peptidases progress?

### From endopeptidases to exopeptidases and hydrophobic to charged

## Step1: Identify the initial type of peptidases### Gastric, pancreatic, and intestinal mucosa initially produce endopeptidases. These enzymes cleave peptide bonds within the peptide chain, starting from the inner part of the peptide.## Step2: Determine the progression in peptidase activity### As the digestive process progresses, the mucosa produce exopeptidases. These enzymes cleave peptide bonds at the outer ends of the peptide chain, facilitating the final breakdown of peptides into amino acids.## Step3: Analyze the charge of peptidases### Initially, the peptidases are hydrophobic, meaning they repel water. As the digestive process continues, these peptidases become charged, allowing them to interact better with the aqueous environment of the digestive tract.