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30/30 Kelebihan dari pemberian obat melalui rute transdermal (melalui kulit) adalah: Efek obot tidak stobil. Hanyo cocok untuk obat-obaton call Menyebabkan rasa sakit podo
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30/30 Kelebihan dari pemberian obat melalui rute transdermal (melalui kulit) adalah: Efek obot tidak stobil. Hanyo cocok untuk obat-obaton call Menyebabkan rasa sakit podo posien. Menghindari metabolisme hot pertomo kall (first-pass metabolism). Efek obat mungkan terjadi terlolu cepot.

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Jawaban

Menghindari metabolisme hot pertomo kall (first-pass metabolism).

Penjelasan

Pemberian obat melalui rute transdermal (melalui kulit) memiliki beberapa kelebihan, salah satunya adalah dapat menghindari metabolisme obat pertama kali (first-pass metabolism). Metabolisme obat pertama kali terjadi ketika obat yang diberikan melalui rute oral melewati hati sebelum mencapai sirkulasi sistemik. Proses ini dapat mengurangi efektivitas obat karena sejumlah obat akan diubah atau dipecah sebelum mencapai konsentrasi efektif di sirkulasi. Dengan memberikan obat melalui rute transdermal, obat akan langsung masuk ke sirkulasi sistemik tanpa melewati hati, sehingga menghindari metabolisme obat pertama kali.
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