Pertanyaan
Angiotensin -converting enzyme (ACE) inhibitors digunakan pada gagal jantung kongestif untuk: Mengurangi remodelling jantung Meningkatkan fungsi jantung Menurunkan tekanan darah Semua jawaban benar
Jawaban
Berikut penjelasannya:
* Mengurangi remodelling jantung: ACE inhibitor membantu mengurangi remodelling jantung dengan menghambat konversi angiotensin I menjadi angiotensin II. Angiotensin II merupakan vasokonstriktor kuat yang dapat menyebabkan hipertrofi dan fibrosis miokard, yang merupakan ciri khas remodelling jantung. Dengan menghambat angiotensin II, ACE inhibitor membantu mencegah kerusakan jantung dan meningkatkan fungsi jantung.
* Meningkatkan fungsi jantung: ACE inhibitor meningkatkan fungsi jantung dengan mengurangi beban kerja jantung. Dengan menurunkan tekanan darah dan mengurangi resistensi pembuluh darah, ACE inhibitor mengurangi beban kerja jantung dan meningkatkan aliran darah ke jantung.
* Menurunkan tekanan darah: ACE inhibitor merupakan obat antihipertensi yang efektif. Dengan menghambat konversi angiotensin I menjadi angiotensin II, ACE inhibitor menyebabkan vasodilatasi dan menurunkan tekanan darah.
Oleh karena itu, ACE inhibitor digunakan pada gagal jantung kongestif untuk mengurangi remodelling jantung, meningkatkan fungsi jantung, dan menurunkan tekanan darah.
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